Labetalol Injection and Zolmitriptan Nasal Spray
Determining the interaction of Labetalol Injection and Zolmitriptan Nasal Spray and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:After one week of dosing with zolmitriptan and propranolol 160 mg/day, the Cmax and AUC of zolmitriptan increased 1.5 times while the Cmax and AUC of the N-desmethyl metabolite decreased by 30% and 15%, respectively. The mechanism of the interaction has not been described. No effects on blood pressure or pulse rate were noted. It does not appear that any special precautions are necessary when coadministering zolmitriptan with beta-blockers, although further post-marketing studies will help to define this interaction.
- "Product Information. Zomig (zolmitriptan)." Zeneca Pharmaceuticals, Wilmington, DE.
Generic Name: labetalol
Brand name: Trandate, Normodyne
Synonyms: Labetalol
Generic Name: zolmitriptan
Brand name: Zomig, Zomig-ZMT
Synonyms: Zolmitriptan, ZOLMitriptan
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Labetalol Injection-Zolmitriptan ODT
- Labetalol Injection-Zolmitriptan Orally Disintegrating Tablets
- Labetalol Injection-Zolmitriptan Tablets
- Labetalol Injection-Zoloft
- Labetalol Injection-Zoloft (Sertraline Oral Liquid)
- Labetalol Injection-Zoloft (Sertraline Tablets)
- Zolmitriptan Nasal Spray-Labetalol Intravenous
- Zolmitriptan Nasal Spray-Labetalol Tablets
- Zolmitriptan Nasal Spray-Lacosamide
- Zolmitriptan Nasal Spray-Lacosamide Injection
- Zolmitriptan Nasal Spray-Lacosamide Intravenous
- Zolmitriptan Nasal Spray-Lacosamide Oral Solution