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Lactulose and OsmoPrep

Determining the interaction of Lactulose and OsmoPrep and the possibility of their joint administration.

Check result:
Lactulose <> OsmoPrep
Relevance: 24.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

If you are using lactulose for the treatment of a condition known as portal-systemic encephalopathy, you should talk to your doctor before using it with sodium phosphate. The loose stools produced by treatment with sodium phosphate may make it difficult to know when you have achieved an adequate dosage of lactulose. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: In the treatment of portal-systemic encephalopathy, the loose stools produced by concomitant use of other laxatives may falsely suggest that adequate lactulose dosage has been achieved.

MANAGEMENT: The use of other laxatives should generally be avoided when lactulose is prescribed for portal-systemic encephalopathy, especially during the initial phase of therapy.

References
  • "Product Information. Cephulac (lactulose)." Hoechst Marion-Roussel Inc, Kansas City, MO.
  • "Product Information. Generlac (lactulose)." Morton Grove Pharmaceuticals Inc, Morton Grove, IL.
  • "Product Information. Enulose (lactulose)." United Research Laboratories/Mutual Pharmaceutical Company, Philadelphia, PA.
  • "Product Information. Chronulac (lactulose)." Hoechst Marion-Roussel Inc, Kansas City, MO.
Lactulose

Generic Name: lactulose

Brand name: Constulose, Kristalose, Chronulac, Cephulac, Constilac, Cholac, Duphalac, Evalose, Heptalac, Enulose, Generlac

Synonyms: n.a.

OsmoPrep

Generic Name: sodium biphosphate / sodium phosphate

Brand name: OsmoPrep, Disposable Enema, Fleet Enema

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction