Lamivudine and zidovudine and Lorazepam Oral Concentrate
Determining the interaction of Lamivudine and zidovudine and Lorazepam Oral Concentrate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One study has suggested that patients receiving zidovudine and a benzodiazepine concomitantly may demonstrate increased plasma clearance of the benzodiazepine. That study also has suggested that patients on concomitant therapy may experience an increased number of headaches. Oxazepam was the only benzodiazepine specifically implicated. However, other benzodiazepines also may participate in this interaction.
- Mole L, Israelski D, Bubp J, O'Hanley P, Merigan T, Blaschke T "Pharmacokinetics of zidovudine alone and in combination with oxazepam in the HIV infected patient." J Acquir Immune Defic Syndr 6 (1993): 56-60
Generic Name: lamivudine / zidovudine
Brand name: Combivir
Synonyms: Lamivudine and Zidovudine
Generic Name: lorazepam
Brand name: Ativan, Lorazepam Intensol
Synonyms: Lorazepam, LORazepam
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Lamivudine and zidovudine-Lorazepam Oral Solution
- Lamivudine and zidovudine-Lorazepam Tablets
- Lamivudine and zidovudine-Lorbrena
- Lamivudine and zidovudine-Lorcaserin
- Lamivudine and zidovudine-Lorcaserin Extended-Release Tablets
- Lamivudine and zidovudine-Lorcaserin Hydrochloride
- Lorazepam Oral Concentrate-Lamivudine and Zidovudine Tablets
- Lorazepam Oral Concentrate-Lamivudine Oral Solution
- Lorazepam Oral Concentrate-Lamivudine Tablets
- Lorazepam Oral Concentrate-Lamotrigine
- Lorazepam Oral Concentrate-Lamotrigine Chewable Dispersible Tablets
- Lorazepam Oral Concentrate-Lamotrigine Chewable Tablet