Lamivudine and Zidovudine Tablets and Leader Heartburn Relief
Determining the interaction of Lamivudine and Zidovudine Tablets and Leader Heartburn Relief and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Cimetidine has been shown to significantly decrease (by 56%) the renal clearance of zidovudine, most likely by competition for active tubular secretion. However, serum levels of zidovudine and its primary metabolite were not affected. Since zidovudine is mostly metabolized by the liver this interaction is unlikely to be of clinical significance except in patients with hepatic impairment.
- Fletcher CV, Henry WK, Noormohamed SE, Rhame FS, Balfour HH "The effect of cimetidine and ranitidine administration with zidovudine." Pharmacotherapy 15 (1995): 701-8
Generic Name: lamivudine / zidovudine
Brand name: Combivir
Synonyms: Lamivudine and zidovudine, Lamivudine and Zidovudine
Generic Name: cimetidine
Brand name: Tagamet HB, Tagamet
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Lamivudine and Zidovudine Tablets-Leader Nicotine Polacrilex gum, lozenge
- Lamivudine and Zidovudine Tablets-Leader Sleep Aid
- Lamivudine and Zidovudine Tablets-Ledipasvir and sofosbuvir
- Lamivudine and Zidovudine Tablets-Ledipasvir and Sofosbuvir Tablets
- Lamivudine and Zidovudine Tablets-Leena
- Lamivudine and Zidovudine Tablets-Lefamulin
- Leader Heartburn Relief-Lamivudine Oral Solution
- Leader Heartburn Relief-Lamivudine Tablets
- Leader Heartburn Relief-Lamotrigine
- Leader Heartburn Relief-Lamotrigine Chewable Dispersible Tablets
- Leader Heartburn Relief-Lamotrigine Chewable Tablet
- Leader Heartburn Relief-Lamotrigine Extended Release Tablet