Lamivudine and Zidovudine Tablets and Onfi (Clobazam Tablets)
Determining the interaction of Lamivudine and Zidovudine Tablets and Onfi (Clobazam Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One study has suggested that patients receiving zidovudine and a benzodiazepine concomitantly may demonstrate increased plasma clearance of the benzodiazepine. That study also has suggested that patients on concomitant therapy may experience an increased number of headaches. Oxazepam was the only benzodiazepine specifically implicated. However, other benzodiazepines also may participate in this interaction.
- Mole L, Israelski D, Bubp J, O'Hanley P, Merigan T, Blaschke T "Pharmacokinetics of zidovudine alone and in combination with oxazepam in the HIV infected patient." J Acquir Immune Defic Syndr 6 (1993): 56-60
Generic Name: lamivudine / zidovudine
Brand name: Combivir
Synonyms: Lamivudine and zidovudine, Lamivudine and Zidovudine
Generic Name: clobazam
Brand name: Onfi, Sympazan
Synonyms: Onfi, Onfi Tablets
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Lamivudine and Zidovudine Tablets-Onfi Tablets
- Lamivudine and Zidovudine Tablets-Onglyza
- Lamivudine and Zidovudine Tablets-Onivyde
- Lamivudine and Zidovudine Tablets-Onmel
- Lamivudine and Zidovudine Tablets-Onset Forte
- Lamivudine and Zidovudine Tablets-Onsolis
- Onfi (Clobazam Tablets)-Lamivudine Oral Solution
- Onfi (Clobazam Tablets)-Lamivudine Tablets
- Onfi (Clobazam Tablets)-Lamotrigine
- Onfi (Clobazam Tablets)-Lamotrigine Chewable Dispersible Tablets
- Onfi (Clobazam Tablets)-Lamotrigine Chewable Tablet
- Onfi (Clobazam Tablets)-Lamotrigine Extended Release Tablet