Lamotrigine Tablets and Pyrimethamine and sulfadoxine
Determining the interaction of Lamotrigine Tablets and Pyrimethamine and sulfadoxine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using pyrimethamine together with sulfadoxine can increase your risk of anemias. Contact your doctor if you experience any changes in your blood test or if you feel weak or fatigued. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration of pyrimethamine in doses exceeding 25 mg per week with trimethoprim or sulfonamides may increase the risk of megaloblastic anemia and pancytopenia. The proposed mechanism is additive antifolate effects.
MANAGEMENT: Periodic clinical and laboratory monitoring for signs of folic acid deficiency and hematologic changes is advisable.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Multum Information Services, Inc. Expert Review Panel"
Generic Name: lamotrigine
Brand name: Lamictal, Lamictal ODT, Lamictal XR, Subvenite, Lamictal CD, LaMICtal Starter Kit, LaMICtal ODT Patient Titration Kit, LaMICtal XR Patient Titration Kit, LamoTRIgine Starter Kit, Subvenite Starter Kit, Lamictal, Lamictal ODT, Lamictal XR
Synonyms: Lamotrigine, LamoTRIgine
Generic Name: pyrimethamine / sulfadoxine
Brand name:
Synonyms: Pyrimethamine and sulfadoxine (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Lamotrigine Tablets-Pyrophosphate Injection
- Pyrimethamine and sulfadoxine-Lamprene
- Pyrimethamine and sulfadoxine-Lanacane
- Pyrimethamine and sulfadoxine-Land Before Time Multivitamin OR CHEW w/Extra C & FA
- Pyrimethamine and sulfadoxine-Lanoxicaps
- Pyrimethamine and sulfadoxine-Lanoxin
- Pyrimethamine and sulfadoxine-Lanoxin (Digoxin Injection)