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Lanoxin and Tegaserod

Determining the interaction of Lanoxin and Tegaserod and the possibility of their joint administration.

Check result:

Lanoxin <> Tegaserod

Relevance: 08.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Tegaserod slightly decreased digoxin plasma concentrations and AUC in a clinical study (n=12); however the changes were considered clinically insignificant. The mechanism is unknown. No action is necessary.

References

"Product Information. Zelnorm (tegaserod)." Novartis Pharmaceuticals, East Hanover, NJ.
Zhou H, Horowitz A, Ledford PC, et al. "The effects of tegaserod (HTF 919) on the pharmacokinetics and pharmacodynamics of digoxin in healthy subjects." J Clin Pharmacol 41 (2001): 1131-9

Lanoxin

Generic Name: digoxin

Brand name: Lanoxin, Digitek, Digox, Lanoxicaps, Cardoxin

Synonyms: n.a.

What is Lanoxin?

Tegaserod

Generic Name: tegaserod

Brand name: Zelnorm

Synonyms: Tegaserod Maleate

What is Tegaserod?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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