Lanoxin (Digoxin Injection) and Topamax (Topiramate Tablets)
Determining the interaction of Lanoxin (Digoxin Injection) and Topamax (Topiramate Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:In a single-dose study, the serum digoxin area under the curve was decreased by 12% when coadministered with topiramate. The mechanism and clinical significance of this interaction is unknown. Serum digoxin levels and clinical response should be monitored. Patients should be advised to notify their physician if they experience worsening heart symptoms.
- "Product Information. Topamax (topiramate)." Ortho Pharmaceutical Corporation, Raritan, NJ.
Generic Name: digoxin
Brand name: Lanoxin, Digitek, Digox, Lanoxicaps, Cardoxin
Synonyms: Lanoxin
Generic Name: topiramate
Brand name: Qudexy XR, Topamax, Topamax Sprinkle, Topiragen, Trokendi XR, Qudexy XR Sprinkle
Synonyms: Topamax
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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