Lanoxin Intravenous and Tirosint-Sol
Determining the interaction of Lanoxin Intravenous and Tirosint-Sol and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Before taking levothyroxine, tell your doctor if you also use digoxin. You may need dose adjustments or special tests in order to safely take both medications together. This combination may cause a decrease in digoxin levels. The dosage of digoxin may need to be increased. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor first.
Professional:MONITOR: The clearance of or sensitivity to digitalis glycosides may be increased in previously hypothyroid patients when a euthyroid state is achieved after the addition of thyroid hormones.
MANAGEMENT: Monitor the patient closely for altered efficacy and safety while achieving a euthyroid state or when thyroid hormones are added, discontinued, or dosing changes are made. Digitalis dose increases may be required.
- Frye RL, Braunwald E "Studies on digitalis. III: The influence of triiodothyronine on digitalis requirements." Circulation 23 (1961): 376-82
- Lawrence JR, Sumner DJ, Kalk WJ, et al "Digoxin kinetics in patients with thyroid dysfunction." Clin Pharmacol Ther 22 (1977): 7-13
- Huffman DH, Klaassen CD, Hartman CR "Digoxin in hyperthyroidism." Clin Pharmacol Ther 22 (1977): 533-8
Generic Name: digoxin
Brand name: Lanoxin, Digitek, Digox, Lanoxicaps, Cardoxin
Synonyms: Lanoxin
Generic Name: levothyroxine
Brand name: Tirosint-Sol, Euthyrox, Levoxyl, Synthroid, Tirosint, Unithroid, Levothroid
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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- Tirosint-Sol-Lanoxin Tablets
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- Tirosint-Sol-Lanreotide Subcutaneous