Drug search by name

Lanoxin Pediatric and Tagamet HB

Determining the interaction of Lanoxin Pediatric and Tagamet HB and the possibility of their joint administration.

Check result:

Lanoxin Pediatric <> Tagamet HB

Relevance: 04.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Both increases and decreases in serum digoxin concentrations have been reported following the administration of cimetidine. Other studies have failed to document any changes in digoxin pharmacokinetics during concomitant therapy. The clinical significance of this interaction has yet to be elucidated. Cimetidine may interact with digitoxin in a similar manner.

References

Crome P, Curl B, Holt D, Volans GN, Bennett PN, Cole DS "Digoxin and cimetidine: investigation of the potential for a drug interaction." Hum Toxicol 4 (1985): 391-9
Mouser B, Nykamp D, Murphy JE, Krissman PH "Effect of cimetidine on oral digoxin absorption." DICP 24 (1990): 286-8
Garty M, Perry G, Shmueli H, et al "Effect of cimetidine on digoxin disposition in peptic ulcer patients." Eur J Clin Pharmacol 30 (1986): 489-91
Fraley DS, Britton HL, Schwinghammer TL, Kalla R "Effect of cimetidine on steady-state serum digoxin concentrations." Clin Pharm 2 (1983): 163-5
Baciewicz AM, Baciewicz FA "Effect of cimetidine and ranitidine on cardiovascular drugs." Am Heart J 118 (1989): 144-54

Lanoxin Pediatric

Generic Name: digoxin

Brand name: Lanoxin, Digitek, Digox, Lanoxicaps, Cardoxin

Synonyms: Lanoxin

What is Lanoxin Pediatric?

Tagamet HB

Generic Name: cimetidine

Brand name: Tagamet HB, Tagamet

Synonyms: n.a.

What is Tagamet HB?

+ Add a drug Remove all

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

The list of popular interactions