Lanoxin Pediatric Intravenous and Propylthiouracil
Determining the interaction of Lanoxin Pediatric Intravenous and Propylthiouracil and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using digoxin together with propylthiouracil may increase the effects of digoxin. Contact your doctor if you experience nausea, vomiting, decreased appetite, diarrhea, confusion, seizures, hallucinations, light "halos" around objects, green or yellow vision, fatigue, irregular heartbeats, and abnormally fast or slow heartbeats. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The clearance of digitalis glycosides may be reduced when a euthyroid state is achieved after the addition of antithyroid agents.
MANAGEMENT: Monitor the patient closely for altered efficacy and safety while achieving a euthyroid state or when antithyroid agents are added, discontinued, or dosing changes are made. Digitalis dose reductions may be required.
- "Product Information. Tapazole (methimazole)." King Pharmaceuticals Inc, Bristol, TN.
- "Product Information. Propylthiouracil (propylthiouracil)." Lederle Laboratories, Wayne, NJ.
- Frye RL, Braunwald E "Studies on digitalis. III: The influence of triiodothyronine on digitalis requirements." Circulation 23 (1961): 376-82
- Doherty JE, Perkins WH "Digoxin metabolism in hypo- and hyperthyroidism. Studies with tritiated digoxin in thyroid disease." Ann Intern Med 64 (1966): 489-507
Generic Name: digoxin
Brand name: Lanoxin, Digitek, Digox, Lanoxicaps, Cardoxin
Synonyms: Lanoxin
Generic Name: propylthiouracil
Brand name:
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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