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Lansoprazole and Sucralfate Tablets

Determining the interaction of Lansoprazole and Sucralfate Tablets and the possibility of their joint administration.

Check result:
Lansoprazole <> Sucralfate Tablets
Relevance: 04.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using sucralfate together with lansoprazole may decrease the effects of lansoprazole. Lansoprazole should be administered at least 1 hour before or after sucralfate. If your doctor does prescribe these medications together, you may need a dose adjustment to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Coadministration with sucralfate may delay absorption and reduce the bioavailability of lansoprazole by as much as 30%. The exact mechanism of the interaction is unknown, but may involve adsorption of lansoprazole to sucralfate in the gastrointestinal tract.

MANAGEMENT: Some authorities recommend giving lansoprazole at least 1 hour before or after sucralfate administration.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • Cerner Multum, Inc. "Australian Product Information." O 0
  • "Product Information. Prevacid (lansoprazole)." TAP Pharmaceuticals Inc, Deerfield, IL.
Lansoprazole

Generic Name: lansoprazole

Brand name: FIRST Lansoprazole, Prevacid, Prevacid OTC, Prevacid SoluTab

Synonyms: n.a.

Sucralfate Tablets

Generic Name: sucralfate

Brand name: Carafate

Synonyms: Sucralfate

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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