Lantus and Regitine
Determining the interaction of Lantus and Regitine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Phentolamine can increase the endogenous secretion of insulin in patients with type II diabetes mellitus. Theoretically, this effect could decrease insulin requirements. However, since phentolamine is usually administered only in single doses, the clinical importance is probably limited. Management consists of carefully monitoring blood glucose after the administration of phentolamine if the situation warrants.
- Linde J, Deckert T "Increase of insulin concentration in maturity-onset diabetics by phentolamine (Regitine) infusion." Horm Metab Res 5 (1973): 391-5
- Persson I, Larsen L "Serum insulin concentration after alpha-adrenergic blockade and secretin in diabetics." Acta Endocrinol (Copenh) 71 (1972): 331-7
Generic Name: insulin glargine
Brand name: Lantus, Lantus Solostar Pen, Basaglar KwikPen, Toujeo SoloStar, Lantus OptiClik Cartridge, Toujeo Max SoloStar, Lantus SoloStar
Synonyms: n.a.
Generic Name: phentolamine
Brand name: OraVerse
Synonyms: Regitine (Injection)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Lantus-Reglan
- Lantus-Reglan (Metoclopramide Injection Solution)
- Lantus-Reglan (Metoclopramide Tablets)
- Lantus-Reglan Intravenous
- Lantus-Reglan Tablets
- Lantus-Regonol
- Regitine-Lantus SoloStar
- Regitine-Lantus SoloStar (Insulin Glargine (U-100) Cartridge Systems and Pens)
- Regitine-Lantus Solostar (Insulin Glargine (U-300) Pens)
- Regitine-Lantus Solostar Pen
- Regitine-Lapatinib
- Regitine-Lapatinib Ditosylate