Lapatinib Ditosylate and Rifamycin Sodium

• Generic Name: lapatinib
• Dosage Forms: n.a.
• Other Brand Names: Tykerb

In combination with letrozole for treatment of hormone receptor-positive metastatic breast cancer that overexpresses the human epidermal receptor type 2 (HER2) protein in postmenopausal women who are candidates for hormonal therapy. Combined therapy with lapatinib and an aromatase inhibitor has not been compared with trastuzumab-containing chemotherapy for treatment of metastatic breast cancer.

In combination with capecitabine for treatment of advanced or metastatic breast cancer in patients whose tumors overexpress HER2 and who have received prior therapy including an anthracycline, a taxane, and trastuzumab.

• Generic Name: rifamycin
• Dosage Forms: n.a.
• Other Brand Names: Aemcolo

Rifamycin sodium is a rifamycin antibacterial indicated for the treatment of travelers' diarrhea caused by noninvasive strains of Escherichia coli in adults.

Rifamycin sodium is not recommended for use in patients with diarrhea complicated by fever and/or bloody stool or due to pathogens other than noninvasive strains of E. coli.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of rifamycin sodium and other antibacterial drugs, rifamycin sodium should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.