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Larin Fe 1.5/30 and Tegaserod

Determining the interaction of Larin Fe 1.5/30 and Tegaserod and the possibility of their joint administration.

Check result:

Larin Fe 1.5/30 <> Tegaserod

Relevance: 21.02.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Tegaserod decreased levonorgestrel plasma concentrations by less than 10% in a clinical study with a low-dose triphasic oral contraceptive (n=45). The mechanism is unknown. There were no changes in ethinyl estradiol concentrations or in contraceptive efficacy. No action is necessary.

References

Vickers AE, Zollinger M, Dannecker R, Tynes R, Heitz F, Fischer V "In vitro metabolism of tegaserod in human liver and intestine: assessment of drug interactions." Drug Metab Dispos 29 (2001): 1269-76
"Product Information. Zelnorm (tegaserod)." Novartis Pharmaceuticals, East Hanover, NJ.

Larin Fe 1.5/30

Generic Name: ethinyl estradiol / norethindrone

Brand name: Blisovi 24 Fe, Blisovi Fe 15/30, Blisovi Fe 1/20, Estrostep Fe, Gildess 24 Fe, Gildess Fe 15/30, Gildess Fe 1/20, Junel Fe 15/30, Junel Fe 1/20, Junel Fe 24, Larin 24 Fe, Larin Fe 15/30, Larin Fe 1/20, Lo Loestrin Fe, Loestrin 24 Fe, Loestrin Fe 15/30, Loestrin Fe 1/20, Lomedia 24 Fe, Microgestin 24 Fe, Microgestin Fe 15/30, Microgestin Fe 1/20, Tarina Fe 1/20, Taytulla, Tilia Fe, Tri-Legest Fe, Blisovi 24 Fe, Femcon Fe, Kaitlib FE, Lo Minastrin Fe, Microgestin 24 Fe, Norinyl 1+35, Ortho-Novum 7/7/7, Tri-Norinyl, Zenchent, femhrt 05 mg/25 mcg, Fyavolv, Jevantique Lo, Jinteli, Femcon Fe, Generess FE, Loestrin 1/20, Ovcon 35, Brevicon

Synonyms: n.a.

What is Larin Fe 1.5/30?

Tegaserod

Generic Name: tegaserod

Brand name: Zelnorm

Synonyms: Tegaserod Maleate

What is Tegaserod?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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