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Laronidase and Novocain

Determining the interaction of Laronidase and Novocain and the possibility of their joint administration.

Check result:

Laronidase <> Novocain

Relevance: 25.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

The concomitant administration of chloroquine or procaine may theoretically reduce the therapeutic efficacy of laronidase. These lysosomotropic amines may interfere with the intracellular uptake of laronidase by lysosomes. The clinical significance is unknown.

References

Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports. Available from: URL: http://www.ema.europa.eu/ema/index.jsp?curl=pages/includes/medicines/medicines_landingpage.jsp&mid."
Canadian Pharmacists Association "e-CPS. Available from: URL: http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink."

Laronidase

Generic Name: laronidase

Brand name: Aldurazyme

Synonyms: n.a.

What is Laronidase?

Novocain

Generic Name: procaine

Brand name: Novocain

Synonyms: n.a.

What is Novocain?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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