Larotrectinib Sulfate and Robafen Cough Liquidgels

• Generic Name: larotrectinib
• Dosage Forms: n.a.
• Other Brand Names: Vitrakvi

Treatment of solid tumors harboring an NTRK fusion (without a known acquired mutation for resistance) in patients who have metastatic disease or may experience severe morbidity following surgical resection and whose disease progressed following prior therapy or those who are not candidates for other treatment options (designated an orphan drug by FDA for these cancers).

Accelerated approval based on overall response rate and duration of response. Continued approval may be contingent on verification and description of clinical benefit in confirmatory studies.

Confirmation of the presence of NTRK fusion is necessary prior to initiation of therapy. In clinical studies, NTRK fusion status of tumor specimens was determined by fluorescence in situ hybridization (FISH), reverse transcription-polymerase chain reaction (RT-PCR), or next-generation sequencing (NGS).

• Generic Name: dextromethorphan
• Dosage Forms: n.a.
• Other Brand Names: Babee Cof, Buckleys Mixture, Creomulsion, DayQuil Cough, Delsym, Robafen Cough Liquidgels, Scot-Tussin Diabetic, Silphen DM, Benylin DM Pediatric, Creo-Terpin, Delsym 12 Hour Cough Relief, Elixsure Cough, Robitussin CoughGels, St. Joseph Cough Suppressant, Sucrets DM Cough, Theraflu Thin Strips Cough, Triaminic Long Acting Cough, DexAlone, Hold, Sucrets 4-Hour Cough Drops, Robitussin Maximum Strength, Vicks Formula 44

Robafen Cough Liquidgels is a cough suppressant that is used to treat cough caused by the common cold or flu.

Robafen Cough Liquidgels will not treat a cough caused by smoking, asthma, or emphysema.

There are many brands and forms of dextromethorphan available. Not all brands are listed on this leaflet.

Robafen Cough Liquidgels may also be used for purposes not listed in this medication guide.