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Lasix and Tamsulosin Capsules

Determining the interaction of Lasix and Tamsulosin Capsules and the possibility of their joint administration.

Check result:
Lasix <> Tamsulosin Capsules
Relevance: 14.08.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration of furosemide and tamsulosin appears to have no significant effects on either drug. In ten healthy volunteers, administration of a single 20 mg intravenous dose of furosemide in combination with tamsulosin 0.8 mg/day to steady state had no effect on the pharmacodynamics of furosemide as measured by excretion of electrolytes. While furosemide produced an 11% to 12% reduction in tamsulosin peak plasma concentration (Cmax) and systemic exposure (AUC), these changes are not expected to be clinically significant and do not require adjustment of the tamsulosin dosage.

References
  • "Product Information. Flomax (tamsulosin)." Boehringer-Ingelheim, Ridgefield, CT.
Lasix

Generic Name: furosemide

Brand name: Lasix, Diaqua-2, Lo-Aqua

Synonyms: n.a.

Tamsulosin Capsules

Generic Name: tamsulosin

Brand name: Flomax

Synonyms: Tamsulosin

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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