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Lasix and Truxophyllin

Determining the interaction of Lasix and Truxophyllin and the possibility of their joint administration.

Check result:

Lasix <> Truxophyllin

Relevance: 14.08.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Furosemide has reportedly increased, decreased, or not affected serum theophylline levels. The mechanism and clinical significance is unknown. Dosage adjustments may be required if an interaction is suspected.

References

Conlon PF, Grambau GR, Johnson CE, Weg JG "Effect of intravenous furosemide on serum theophylline concentration." Am J Hosp Pharm 38 (1981): 1345-7
Sigurd B, Olesen KH "The supra-additive natriuretic effect addition of theophylline ethylenediamine and bumetanide in congestive heart failure. Permutation trial tests in patients in long-term treatment with bumetanide." Am Heart J 94 (1977): 168-74
Toback JW, Gilman ME "Theophylline-furosemide inactivation?" Pediatrics 71 (1983): 140-1
Upton RA "Pharmacokinetic interactions between theophylline and other medication (Part II)." Clin Pharmacokinet 20 (1991): 135-50
Carpentiere G, Marino S, Castello F "Furosemide and theophylline." Ann Intern Med 103 (1985): 957

Lasix

Generic Name: furosemide

Brand name: Lasix, Diaqua-2, Lo-Aqua

Synonyms: n.a.

What is Lasix?

Truxophyllin

Generic Name: theophylline

Brand name: Elixophyllin, Theo-24, Respbid, T-Phyl, Aerolate III, Slo-Bid Gyrocaps, Slo-Phyllin, Theobid, Theo-Dur, Theolair, Theovent, Bronkodyl, Theo-X, Theo-Time, Theochron, Slo-Phyllin 125, Theoclear LA-130, Aerolate JR, Theolair-SR, Theoclear LA-260, Quibron-T, Quibron-T/SR, Uniphyl, Uni-Dur, Aerolate SR, Slo-Phyllin 80, Theoclear-80, Theo-Dur Sprinkles, Theosol-80, Asmalix, Aquaphyllin, Truxophyllin, Slo-Phyllin 250, TheoCap

Synonyms: Truxophyllin (Oral)

What is Truxophyllin?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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