Leader Acid Control and Mapap Infants
Determining the interaction of Leader Acid Control and Mapap Infants and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Animal studies have suggested that ranitidine may potentiate the hepatotoxicity of acetaminophen, however, a double-blind placebo-controlled crossover study has failed to confirm this finding in humans. Acetaminophen dosage adjustments are not indicated.
- Rogers SA, Gale KC, Newton JF, et al "Inhibition by ranitidine of acetaminophen conjugation and its possible role in ranitidine potentiation of acetaminophen-induced hepatotoxicity." J Pharmacol Exp Ther 245 (1988): 887-94
- Jack D, Thomas M, Skidmore IF "Ranitidine and paracetamol metabolism." Lancet 2 (1985): 1067
Generic Name: ranitidine
Brand name: Zantac
Synonyms: Ranitidine
Generic Name: acetaminophen
Brand name: Mapap Infants, Tylenol Infants, Acephen, Feverall, Mapap, Actamin, Anacin AF, Apra, Bromo Seltzer, Children's Tylenol, Elixsure Fever/Pain, Medi-Tabs, Q-Pap, Silapap Childrens, Tactinal, Tempra Quicklets, Tycolene, Tylenol, Vitapap, Children's Silapap, Febrol Solution, Triaminic Fever Reducer, Genapap, Tylenol Junior, Children's Tylenol Meltaways, Junior Tylenol Meltaways, Ofirmev, Tylenol 8 Hour, Tylenol Arthritis Pain, Tylophen
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Leader Acid Control-Mapap PM
- Leader Acid Control-Mapap rectal
- Leader Acid Control-Mapap Sinus Congestion and Pain
- Leader Acid Control-Maprotiline
- Leader Acid Control-Maprotiline Hydrochloride
- Leader Acid Control-Mar-cof BP
- Mapap Infants-Leader Acid Reducer Maximum Strength
- Mapap Infants-Leader All Day Allergy
- Mapap Infants-Leader Allergy D 12
- Mapap Infants-Leader Allergy Relief
- Mapap Infants-Leader Allergy Relief D-24
- Mapap Infants-Leader Allerhist