Lescol XL and Sylvant

• Generic Name: fluvastatin
• Dosage Forms: tablet, extended release
• Other Brand Names: Lescol, Lescol XL

Lescol XL is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Lescol XL is used to slow the build-up of plaque (fatty deposits) in your blood vessels.

Lescol XL is also used to lower the risk of heart complications in certain people with coronary heart disease.

Lescol XL is used in adults and children who are at least 10 years old.

Lescol XL may also be used for purposes not listed in this medication guide.

• Generic Name: siltuximab
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names: Sylvant

Sylvant (siltuximab) inhibits a certain protein in the body called interleukin-6 (IL-6). High levels of IL-6 can cause an overgrowth of cells in the lymph system (part of your immune system).

Sylvant is used to treat Multicentric Castleman's Disease (MCD). MCD is a rare condition in which the body produces too much of a certain type of white blood cell. MCD can increase your risk of certain cancers by changing the way your immune system works.

Sylvant is not for use in people who have human immunodeficiency virus (HIV) or human herpesvirus-8.