Letrozole and ribociclib and Zometa

• Generic Name: letrozole / ribociclib
• Dosage Forms: n.a.
• Other Brand Names: Kisqali Femara Co-Pack 200 mg-25 mg Dose, Kisqali Femara Co-Pack 400 mg-25 mg Dose, Kisqali Femara Co-Pack 600 mg-25 mg Dose

Letrozole lowers estrogen levels, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.

Ribociclib interferes with the growth and spread of cancer cells in the body.

Letrozole and ribociclib are used together in combination to treat HR-positive, HER2-negative breast cancer in women.

letrozole and ribociclib is used when the cancer has spread to other parts of the body (metastatic).

Letrozole and ribociclib are two different medicines that are packaged together. Letrozole tablets are yellow and ribociclib tablets are violet.

Letrozole and ribociclib may also be used for purposes not listed in this medication guide.

• Generic Name: zoledronic acid
• Dosage Forms: injection, solution, concentrate
• Other Brand Names: Reclast, Zometa, Aclasta, Zometa Concentrate

Zometa (zoledronic acid) (sometimes called zoledronate) is a bisphosphonate medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

Zometa is used to treat high blood levels of calcium caused by cancer (also called hypercalcemia of malignancy). Zometa also treats multiple myeloma (a type of bone marrow cancer) or bone cancer that has spread from elsewhere in the body.

The Reclast brand of zoledronic acid is used in men and women to treat or prevent osteoporosis caused by menopause or by taking steroids. Reclast is also used to increase bone mass in men who have osteoporosis, and to treat Paget's disease of bone in men and women.

You should not use Reclast and Zometa at the same time.