Leucovorin and Zolpidem Tartrate

• Generic Name: leucovorin
• Dosage Forms: n.a.
• Other Brand Names: Wellcovorin

Leucovorin is a form of folic acid. Folic acid helps your body produce and maintain new cells, and also helps prevent changes to DNA that may lead to cancer. Folic acid is present in many foods such as dried beans, peas, oranges, spinach, and others.

Leucovorin is used to reduce the side effects of large doses or accidental overdose of medications that can reduce the effects of folic acid in the body. This includes methotrexate (Rheumatrex), pyrimethamine (Daraprim), trimethoprim (Trimpex, Proloprim), and others.

Leucovorin may also be used for purposes not listed in this medication guide.

• Generic Name: zolpidem
• Dosage Forms: n.a.
• Other Brand Names: Ambien, Ambien CR, Edluar, Intermezzo, ZolpiMist

Conventional tablets, oral spray, or sublingual tablets (Edluar) used for short-term management of insomnia characterized by difficulties with sleep initiation. Decreases sleep latency in patients with chronic or transient insomnia; no substantial evidence of diminished effectiveness during the end of each night’s use (early morning insomnia) despite short half-life.

Extended-release tablets used for management of insomnia characterized by difficulty with sleep onset or sleep maintenance. May not be an appropriate treatment choice for patients (men or women) who need to drive or perform activities that require full alertness the next morning (see CNS Depression and Next-day Impairment under Cautions).

Sublingual tablets (Intermezzo) used as needed for management of insomnia when middle-of-the-night awakening is followed by difficulty returning to sleep; for use only when ≥4 hours remain before planned time of awakening.