Levalbuterol HFA Aerosol and Oxybutynin Chloride

• Generic Name: levalbuterol
• Dosage Forms: aerosol, metered
• Other Brand Names: Xopenex, Xopenex Concentrate, Xopenex HFA

Levalbuterol is a short-acting bronchodilator that relaxes muscles in the airways and increases air flow to the lungs.

Levalbuterol inhalation is used to treat or prevent asthma attacks in adults and children who are at least 4 years old.

Levalbuterol inhalation may also be used for purposes not listed in this medication guide.

• Generic Name: oxybutynin
• Dosage Forms: n.a.
• Other Brand Names: Ditropan XL, Anturol, Gelnique, Oxytrol

Relief of symptoms of bladder instability associated with voiding (i.e., urgency, frequency, urinary leakage, urge incontinence, dysuria) in adults and pediatric patients > 5 years of age with uninhibited neurogenic or reflex neurogenic bladder (conventional tablets or oral solution).

Treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency (extended-release tablets or transdermal system).

Relief of symptoms of detrusor overactivity associated with a neurological condition (e.g., spina bifida) in pediatric patients ≥ 6 years of age (extended-release tablets).

Conventional tablets as effective as extended-release tablets.

Oxybutynin appears to be as effective as tolterodine (conventional tablets) in reducing urinary symptoms in patients with overactive bladder but is associated with a higher incidence of dry mouth.

Has been used in children for the treatment of primary nocturnal enuresis; however one study has determined that oxybutynin is not effective for management of primary nocturnal enuresis in children with a history of nocturnal enuresis and normal bladders.