Levetiracetam Extended-Release Tablets and Methotrexate Sodium
Determining the interaction of Levetiracetam Extended-Release Tablets and Methotrexate Sodium and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with levetiracetam may increase plasma concentrations of methotrexate. Neither the mechanism of interaction nor the clinical significance have been established. Plasma levels of methotrexate should be carefully monitored in patients receiving this combination.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Methotrexate and Methotrexate LPF (methotrexate)." Lederle Laboratories, Wayne, NJ.
- Cerner Multum, Inc. "Australian Product Information." O 0
Generic Name: levetiracetam
Brand name: Keppra, Keppra XR, Roweepra, Spritam, Roweepra XR
Synonyms: Levetiracetam, LevETIRAcetam
Generic Name: methotrexate
Brand name: Otrexup, Rasuvo, Rheumatrex Dose Pack, Trexall, Xatmep, Methotrexate Sodium, Preservative Free
Synonyms: Methotrexate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Levetiracetam Extended-Release Tablets-Methotrexate Tablets
- Levetiracetam Extended-Release Tablets-Methoxsalen
- Levetiracetam Extended-Release Tablets-Methoxsalen (Systemic)
- Levetiracetam Extended-Release Tablets-Methoxsalen (Topical)
- Levetiracetam Extended-Release Tablets-Methoxsalen Extracorporeal Solution
- Levetiracetam Extended-Release Tablets-Methoxsalen Hard-Gelatin Capsules
- Methotrexate Sodium-Levetiracetam Injection
- Methotrexate Sodium-Levetiracetam Injection, Concentrate
- Methotrexate Sodium-Levetiracetam Intravenous
- Methotrexate Sodium-Levetiracetam Oral Solution
- Methotrexate Sodium-Levetiracetam Solution
- Methotrexate Sodium-Levetiracetam Tablets