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Levetiracetam Tablets and Probenecid and colchicine

Determining the interaction of Levetiracetam Tablets and Probenecid and colchicine and the possibility of their joint administration.

Check result:
Levetiracetam Tablets <> Probenecid and colchicine
Relevance: 11.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Probenecid decreases the renal clearance of ucb L057, a metabolite of levetiracetam, by approximately 60%. Although this metabolite has been shown to be inactive in animals, patients should be monitored for adverse effects when these drugs are coadministered.

References
  • "Product Information. Keppra (levetiracetam)" UCB Pharma Inc, Smyrna, GA.
Levetiracetam Tablets

Generic Name: levetiracetam

Brand name: Keppra, Keppra XR, Roweepra, Spritam, Roweepra XR

Synonyms: Levetiracetam, LevETIRAcetam

Probenecid and colchicine

Generic Name: colchicine / probenecid

Brand name:

Synonyms: Probenecid and colchicine (Oral)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.