Levoleucovorin and Zilretta injection

• Generic Name: levoleucovorin
• Dosage Forms: n.a.
• Other Brand Names: Fusilev, Khapzory

Levoleucovorin (Fusilev) is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer.

Levoleucovorin is also used to treat or prevent toxic effects of methotrexate in people whose bodies do not eliminate methotrexate properly after the drug is metabolized. It may also be used to treat toxic effects of an overdose of methotrexate or certain other medications.

Levoleucovorin is also used in combination chemotherapy with fluorouracil to treat colorectal cancer that has spread to other parts of the body. Levoleucovorin treats only the symptoms of colorectal cancer but does not treat the cancer itself.

Levoleucovorin should not be used to treat anemia that is caused by a lack of vitamin B12.

• Generic Name: triamcinolone
• Dosage Forms: extended-release injectable suspension kit
• Other Brand Names: Kenalog-40, Zilretta, Aristocort, Azmacort

Zilretta is a steroid that prevents the release of substances in the body that cause inflammation.

Zilretta is used to treat many different types of inflammatory conditions, including severe allergic reactions, skin disorders, severe colitis, inflammation of the joints or tendons, blood cell disorders, inflammatory eye disorders, lung disorders, and problems caused by low adrenal gland hormones.

Zilretta is also used to treat certain skin disorders caused by autoimmune conditions such as lupus, psoriasis, lichen planus, and others.

Different brands of triamcinolone injection have different uses.

Zilretta may also be used for purposes not listed in this medication guide.