Levomilnacipran Hydrochloride and Sinuva

• Generic Name: levomilnacipran
• Dosage Forms: n.a.
• Other Brand Names: Fetzima

Treatment of major depressive disorder in adults.

APA states that effectiveness of antidepressants is generally comparable between and within classes of medications, including SSRIs, SNRIs, TCAs, MAO inhibitors, and other antidepressants (e.g., bupropion, mirtazapine, trazodone). Choose antidepressant based mainly on the following factors: patient preference; nature of prior response to medication; safety, tolerability, and anticipated adverse effects; concurrent psychiatric and medical conditions; specific properties of the medication (e.g., half-life, actions on CYP isoenzymes, other drug interactions); and cost. For most patients, an SSRI, SNRI, mirtazapine, or bupropion is considered optimal.

Fibromyalgia

Levomilnacipran is the more active 1S,2R-enantiomer of racemic milnacipran (Savella), which is FDA-labeled for use in the management of fibromyalgia.

Manufacturer states that levomilnacipran (Fetzima) is not approved for the management of fibromyalgia; efficacy and safety of the drug for this use not established.

• Generic Name: mometasone nasal
• Dosage Forms: implant
• Other Brand Names: Nasonex, Propel, Sinuva, Propel Mini, Propel Contour

Mometasone is a steroid. It prevents the release of substances in the body that cause inflammation.

Sinuva (for use in the nose) is used to treat nasal symptoms of seasonal or year-round allergies, including congestion, sneezing, and runny nose. This medicine is approved for this use in adults and children who are at least 2 years old.

Sinuva is also used to prevent seasonal allergy symptoms in adults and children who are at least 12 years old.

Sinuva is used to treat nasal polyps only in adults.

Mometasone may also be used for other purposes not listed in this medication guide.