Levonorgestrel and ethinyl estradiol and Lorazepam Oral Concentrate
Determining the interaction of Levonorgestrel and ethinyl estradiol and Lorazepam Oral Concentrate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Oral contraceptives may increase the clearance rate of benzodiazepines that undergo glucuronidation (such as lorazepam, oxazepam, and temazepam). Close observation for signs and symptoms of altered benzodiazepine effect is recommended.
- Scavone JM, Greenblatt DJ, Locniskar A, Shader RI "Alprazolam pharmacokinetics in women on low-dose oral contraceptives." J Clin Pharmacol 28 (1988): 454-7
- Billedeau SM, Holder CL, Getek TA "High-performance liquid chromatography of the antihistamine pyrilamine and its N-oxide using electrochemical detection." J Chromatogr 534 (1990): 151-9
- Patwardhan RV, Mitchell MC, Johnson RF, Schenker S "Differential effects of oral contraceptive steroids on the metabolism of benzodiazepines." Hepatology 3 (1983): 248-53
- Abernethy DR, Greenblatt DJ, Divoll M, Arendt R, Ochs HR, Shader RI "Impairment of diazepam metabolism by low-dose estrogen-containing oral-contraceptive steroids." N Engl J Med 306 (1982): 791-2
- Stoehr GP, Kroboth PD, Juhl RP, Wender DB, Phillips JP, Smith RB "Effect of oral contraceptives on triazolam, temazepam, alprazolam, and lorazepam kinetics." Clin Pharmacol Ther 36 (1984): 683-90
Generic Name: ethinyl estradiol / levonorgestrel
Brand name: Amethyst, Aviane, Balcoltra, Falmina, Levlen, Lillow, Orsythia, Vienva, Afirmelle, Altavera, Amethia, Amethia Lo, Ashlyna, Aubra, Aubra EQ, Ayuna, Camrese, Camrese Lo, Chateal, Chateal EQ, Daysee, Delyla, Enpresse-28, FaLessa, Fayosim, Introvale, Jolessa, Kurvelo, Larissia, Lessina, Levonest, Levora 015/30, LoSeasonique, Lutera, Marlissa, Myzilra, Portia-28, Quartette, Quasense, Rivelsa, Seasonique, Setlakin, Simpesse, Sronyx, Trivora, Alesse, Enpresse, Levora, Lybrel, Nordette, Portia, Tri-Levlen, Triphasil-21, Triphasil-28, Trivora-28, Seasonale, Preven EC, Triphasil
Synonyms: Ethinyl estradiol and levonorgestrel, Ethinyl Estradiol and Levonorgestrel
Generic Name: lorazepam
Brand name: Ativan, Lorazepam Intensol
Synonyms: Lorazepam, LORazepam
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Levonorgestrel and ethinyl estradiol-Lorazepam Oral Solution
- Levonorgestrel and ethinyl estradiol-Lorazepam Tablets
- Levonorgestrel and ethinyl estradiol-Lorbrena
- Levonorgestrel and ethinyl estradiol-Lorcaserin
- Levonorgestrel and ethinyl estradiol-Lorcaserin Extended-Release Tablets
- Levonorgestrel and ethinyl estradiol-Lorcaserin Hydrochloride
- Lorazepam Oral Concentrate-Levonorgestrel emergency contraceptive
- Lorazepam Oral Concentrate-Levonorgestrel Intradermal
- Lorazepam Oral Concentrate-Levonorgestrel Intrauterine
- Lorazepam Oral Concentrate-Levonorgestrel intrauterine system
- Lorazepam Oral Concentrate-Levonorgestrel, ethinyl estradiol, and ferrous bisglycinate
- Lorazepam Oral Concentrate-Levophed