Levonorgestrel and ethinyl estradiol and Welchol (Colesevelam Oral Suspension)
Determining the interaction of Levonorgestrel and ethinyl estradiol and Welchol (Colesevelam Oral Suspension) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using colesevelam together with ethinyl estradiol may decrease the effects of ethinyl estradiol. Ethinyl estradiol should be administered at least 4 hours before colesevelam. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Colesevelam may decrease the gastrointestinal absorption of contraceptive hormones. A 24% reduction in peak plasma concentration (Cmax) and systemic exposure (AUC) has been reported for ethinyl estradiol (0.035 mg), and a 20% reduction in Cmax has been reported for norethindrone (1 mg).
MANAGEMENT: Oral contraceptives containing ethinyl estradiol and norethindrone should be administered at least 4 hours before the colesevelam dose. The same precaution may be applicable to other contraceptive hormones, although data are lacking.
- "Product Information. Welchol (colesevelam)" Daiichi Sankyo, Inc., Parsippany, NJ.
Generic Name: ethinyl estradiol / levonorgestrel
Brand name: Amethyst, Aviane, Balcoltra, Falmina, Levlen, Lillow, Orsythia, Vienva, Afirmelle, Altavera, Amethia, Amethia Lo, Ashlyna, Aubra, Aubra EQ, Ayuna, Camrese, Camrese Lo, Chateal, Chateal EQ, Daysee, Delyla, Enpresse-28, FaLessa, Fayosim, Introvale, Jolessa, Kurvelo, Larissia, Lessina, Levonest, Levora 015/30, LoSeasonique, Lutera, Marlissa, Myzilra, Portia-28, Quartette, Quasense, Rivelsa, Seasonique, Setlakin, Simpesse, Sronyx, Trivora, Alesse, Enpresse, Levora, Lybrel, Nordette, Portia, Tri-Levlen, Triphasil-21, Triphasil-28, Trivora-28, Seasonale, Preven EC, Triphasil
Synonyms: Ethinyl estradiol and levonorgestrel, Ethinyl Estradiol and Levonorgestrel
Generic Name: colesevelam
Brand name: Welchol, Colesevelam Hydrochloride
Synonyms: Welchol
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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