Levophed and Tivorbex

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Limited data have shown that indomethacin may enhance the pressor response to norepinephrine. Eicosanoids originating from the cyclooxygenase pathway of arachidonate metabolism may modulate the vascular response to adrenergic stimulation. Indomethacin is a potent cyclooxygenase inhibitor. The clinical significance is unknown. Blood pressure monitoring is recommended during norepinephrine infusion, particularly in patients who have used or are taking indomethacin.

Levophed

Generic Name: norepinephrine

Brand name: Levophed, Levophed Bitartrate

Synonyms: n.a.

What is Levophed?

Tivorbex

Generic Name: indomethacin

Brand name: Indocin, Indocin SR, Tivorbex

Synonyms: n.a.

What is Tivorbex?