Levothyroxine Injection and Triprolidine and Phenylephrine Syrup
Determining the interaction of Levothyroxine Injection and Triprolidine and Phenylephrine Syrup and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using levothyroxine together with phenylephrine. Combining these medications may increase the risk of cardiovascular side effects such as high blood pressure, palpitation, chest pain, and irregular heart beat. If you have preexisting heart disease, your condition may worsen. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant use of thyroid hormones, especially large doses, with sympathomimetic drugs may potentiate sympathomimetic effects and increase the risk of cardiac insufficiency in patients who have coronary artery disease.
MANAGEMENT: Monitoring for increased sympathomimetic effects and cardiac function may be advisable.
- "Product Information. Synthroid (levothyroxine)." Abbott Pharmaceutical, Abbott Park, IL.
- Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
- "Product Information. Armour thyroid (thyroid desiccated)." Forest Pharmaceuticals, St. Louis, MO.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: levothyroxine
Brand name: Levoxyl, Synthroid, Tirosint, Unithroid, Euthyrox, Levothroid, Tirosint-Sol
Synonyms: Levothyroxine
Generic Name: phenylephrine / triprolidine
Brand name: Prohist LQ, Histex PE, Histex-PE
Synonyms: Phenylephrine and triprolidine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Levothyroxine Injection-Triprolidine and Pseudoephedrine Liquid
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- Levothyroxine Injection-Triprolidine Chewable Tablets
- Levothyroxine Injection-Triprolidine Drops
- Levothyroxine Injection-Triprolidine Hydrochloride
- Levothyroxine Injection-Triprolidine Syrup
- Triprolidine and Phenylephrine Syrup-Levothyroxine Injection Solution
- Triprolidine and Phenylephrine Syrup-Levothyroxine Oral Solution
- Triprolidine and Phenylephrine Syrup-Levothyroxine oral/injection
- Triprolidine and Phenylephrine Syrup-Levothyroxine Sodium
- Triprolidine and Phenylephrine Syrup-Levothyroxine Tablets
- Triprolidine and Phenylephrine Syrup-Levoxyl