Levothyroxine oral/injection and Pyril DM Suspension
Determining the interaction of Levothyroxine oral/injection and Pyril DM Suspension and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using levothyroxine together with phenylephrine. Combining these medications may increase the risk of cardiovascular side effects such as high blood pressure, palpitation, chest pain, and irregular heart beat. If you have preexisting heart disease, your condition may worsen. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant use of thyroid hormones, especially large doses, with sympathomimetic drugs may potentiate sympathomimetic effects and increase the risk of cardiac insufficiency in patients who have coronary artery disease.
MANAGEMENT: Monitoring for increased sympathomimetic effects and cardiac function may be advisable.
- "Product Information. Synthroid (levothyroxine)." Abbott Pharmaceutical, Abbott Park, IL.
- Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
- "Product Information. Armour thyroid (thyroid desiccated)." Forest Pharmaceuticals, St. Louis, MO.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: levothyroxine
Brand name: Levoxyl, Synthroid, Tirosint, Unithroid, Euthyrox, Levothroid, Tirosint-Sol
Synonyms: Levothyroxine
Generic Name: dextromethorphan / phenylephrine / pyrilamine
Brand name: Codal-DM Syrup, Codimal DM, Codituss DM, Poly Hist DM, Viravan-DM, V-Tan DM, Zotex-12, Deconsal DM Tannate, Aldex DM, Viratan-DM, Triplex DM, MyHist-DM, Tannate V DM, Reme Hist DM, Pryil DM, Pyril DM
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Levothyroxine oral/injection-Pyril Mal Phenyl HCl
- Levothyroxine oral/injection-Pyril Mal Phenyl HCl Dex HBr
- Levothyroxine oral/injection-Pyrilamine and Codeine
- Levothyroxine oral/injection-Pyrimethamine
- Levothyroxine oral/injection-Pyrimethamine and sulfadoxine
- Levothyroxine oral/injection-Pyrophosphate Injection
- Pyril DM Suspension-Levothyroxine Sodium
- Pyril DM Suspension-Levothyroxine Tablets
- Pyril DM Suspension-Levoxyl
- Pyril DM Suspension-Levsin
- Pyril DM Suspension-Levsin (Hyoscyamine Injection)
- Pyril DM Suspension-Levsin (Hyoscyamine Tablets)