Levothyroxine Sodium and Prevymis

• Generic Name: levothyroxine
• Dosage Forms: n.a.
• Other Brand Names: Levothroid, Levoxyl, Synthroid, Unithroid, Tirosint, Euthyrox, Tirosint-Sol

Used orally as replacement or supplemental therapy in congenital or acquired hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis. Specific indications include subclinical hypothyroidism and primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) hypothyroidism.

Considered drug of choice for the treatment of congenital hypothyroidism (cretinism).

Used IV for treatment of myxedema coma.

Has been used IV in other conditions when rapid thyroid replacement is required; however, this is not an FDA-labeled use for the currently available injection.

Treatment or prevention of various types of euthyroid goiters, including thyroid nodules, subacute or chronic lymphocytic thyroiditis (Hashimoto’s thyroiditis), and multinodular goiter.

Adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer.

Efficacy of TSH suppression for benign nodular disease remains controversial.

See Unlabeled Uses under Cautions.

• Generic Name: letermovir
• Dosage Forms: tablet, film coated
• Other Brand Names: Prevymis

Prevymis (letermovir) is an antiviral medicine used to help prevent cytomegalovirus (CMV) infection after a stem cell (bone marrow) transplant from a donor.

Prevymis is for use in adults who are seropositive for CMV. Seropositive means that the virus is in your blood even if you do not show any symptoms of infection.

A CMV-seropositive person is at risk for "reactivation" of the virus if the immune system becomes weak. While normally treatable, CMV infection can be serious in people undergoing a stem cell transplant.

Prevymis comes as a tablet or can be given by your doctor through an IV line (intravenously).