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Lidocaine and Myocard-DX

Determining the interaction of Lidocaine and Myocard-DX and the possibility of their joint administration.

Check result:

Lidocaine <> Myocard-DX

Relevance: 17.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Limited data suggest that low dose dopamine (2 mcg/kg/min) increases lidocaine dose requirements to maintain epidural anesthesia by as much as 45% without a significant change in plasma lidocaine concentrations. The mechanism may be related to enhanced hepatic lidocaine elimination. Clinical monitoring of anesthetic response is recommended and lidocaine dosage adjustments may be necessary.

References

Sprung J, Bourke DL, Schoenwald PK, Whalley D, Gottlieb A, Mascha EJ, Kapural L "Small-dose dopamine increases epidural lidocaine requirements during peripheral vascular surgery in elderly patients." Anesth Analg 90 (2000): 388-92

Lidocaine

Generic Name: lidocaine

Brand name: UAD Caine, Xylocaine HCl, Xylocaine-MPF, Lidoject 1, Xylocaine Dental Cartridges, Lidoject 2, Xylocaine Duo-Trach Kit, Xylocaine HCl For Spinal, L-Caine, Dilocaine, Nervocaine, Truxacaine, Anestacaine

Synonyms: Lidocaine injection, Lidocaine (Systemic)

What is Lidocaine?

Myocard-DX

Generic Name: dopamine

Brand name: Intropin

Synonyms: n.a.

What is Myocard-DX?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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