Lidocaine and Tocainide

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using lidocaine together with tocainide may have additive effects. You should start tocainide six hours before stopping lidocaine infusions, then starting the next maintenance dose of tocainide six hours after the lidocaine drip has ended. Your heart rhythm and response should be monitored during this time. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

ADJUST DOSING INTERVAL: Lidocaine and tocainide are structurally similar, and each crosses the blood-brain barrier. Their central nervous system side effects, such as agitation, disorientation, and seizures may be additive.

MANAGEMENT: Management consists of cautiously starting patients on tocainide six hours before stopping lidocaine infusions, then starting the next maintenance dose of tocainide six hours after the lidocaine drip has ended. The patient's heart rhythm and clinical response should be monitored during this time.

Lidocaine

Generic Name: lidocaine

Brand name: UAD Caine, Xylocaine HCl, Xylocaine-MPF, Lidoject 1, Xylocaine Dental Cartridges, Lidoject 2, Xylocaine Duo-Trach Kit, Xylocaine HCl For Spinal, L-Caine, Dilocaine, Nervocaine, Truxacaine, Anestacaine

Synonyms: Lidocaine injection, Lidocaine (Systemic)

What is Lidocaine?

Tocainide

Generic Name: tocainide

Brand name:

Synonyms: Tocainide (Oral)

What is Tocainide?