Lidocaine Hydrochloride and Talimogene laherparepvec

• Generic Name: lidocaine
• Dosage Forms: n.a.
• Other Brand Names: UAD Caine, Xylocaine HCl, Xylocaine-MPF, Lidoject 1, Xylocaine Dental Cartridges, Lidoject 2, Xylocaine Duo-Trach Kit, Xylocaine HCl For Spinal, L-Caine, Dilocaine, Nervocaine, Truxacaine, Anestacaine

Alternative to other antiarrhythmic drugs (e.g., amiodarone, procainamide, sotalol) for the acute treatment of life-threatening ventricular arrhythmias such as those that occur following MI or during cardiac manipulative procedures such as cardiac surgery.

Used during cardiac arrest for treatment of refractory (i.e., resistant to CPR, defibrillation, and a vasopressor [epinephrine]) VF or pulseless VT. Considered an alternative to amiodarone for this use in current ACLS guidelines in adults; in pediatric patients, current evidence supports use of either amiodarone or lidocaine.

Alternative to other antiarrhythmic agents or synchronized electrical cardioversion in the treatment of hemodynamically stable monomorphic VT; however, other agents (e.g., procainamide, sotalol, amiodarone) preferred.

Treatment of status epilepticus, as a last resort.

• Generic Name: talimogene laherparepvec
• Dosage Forms: n.a.
• Other Brand Names: Imlygic

Talimogene laherparepvec is a cancer medicine that affects the actions of the body's immune system, helping the body produce an "antitumor" response. Talimogene laherparepvec is a genetically modified weak form of type 1 herpes simplex virus (the virus that causes common cold sores).

Talimogene laherparepvec is used to treat a type of cancer called melanoma when it is on the skin or in the lymph glands.

Talimogene laherparepvec may also be used for purposes not listed in this medication guide.