Lidocaine Intradermal and Lipodox 50
Determining the interaction of Lidocaine Intradermal and Lipodox 50 and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited in vitro data have shown that the two local anesthetics, procaine and lidocaine, can act synergistically with doxorubicin to inhibit cell growth. Data suggest that clinically achievable concentrations of these drugs could enhance doxorubicin cytotoxicity. The clinical relevance of these data is unknown.
- Chlebowski RT, Block JB, Cundiff D, Dietrich MF "Doxorubicin cytotoxicity enhanced by local anesthetics in a human melanoma cell line." Cancer Treat Rep 66 (1982): 121-125
Generic Name: lidocaine
Brand name: UAD Caine, Xylocaine HCl, Xylocaine-MPF, Lidoject 1, Xylocaine Dental Cartridges, Lidoject 2, Xylocaine Duo-Trach Kit, Xylocaine HCl For Spinal, L-Caine, Dilocaine, Nervocaine, Truxacaine, Anestacaine
Synonyms: Lidocaine injection, Lidocaine (Systemic)
Generic Name: doxorubicin liposomal
Brand name: Doxil, Lipodox 50, Lipodox
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Lidocaine Intradermal-Lipofen
- Lidocaine Intradermal-Liposyn
- Lidocaine Intradermal-Liposyn III
- Lidocaine Intradermal-Liposyn II
- Lidocaine Intradermal-LiproZonePak
- Lidocaine Intradermal-Liptruzet
- Lipodox 50-Lidocaine Intradermal Injection
- Lipodox 50-Lidocaine IV Solution
- Lipodox 50-Lidocaine Jelly
- Lipodox 50-Lidocaine Laryngotracheal Solution
- Lipodox 50-Lidocaine Lotion
- Lipodox 50-Lidocaine Ointment