Lidocaine Topical Oral Solution 4% and Mexitil
Determining the interaction of Lidocaine Topical Oral Solution 4% and Mexitil and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using lidocaine together with mexiletine may increase the effects of lidocaine. This can cause increased side effects or cause your condition to change. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Mexiletine may increase the serum lidocaine levels and toxicity. The mechanism is unknown.
MANAGEMENT: Management consists of monitoring the patient for symptoms of neurotoxicity, monitoring plasma levels and decreasing the lidocaine dosage if an interaction is suspected.
- Christie JM, Valdes C, Markowsky SJ "Neurotoxicity of lidocaine combined with mexiletine." Anesth Analg 77 (1993): 1291-4
- Geraets DR, Scott SD, Ballew KA "Toxicity potential of oral lidocaine in a patient receiving mexiletine." Ann Pharmacother 26 (1992): 1380-1
Generic Name: lidocaine
Brand name: UAD Caine, Xylocaine HCl, Xylocaine-MPF, Lidoject 1, Xylocaine Dental Cartridges, Lidoject 2, Xylocaine Duo-Trach Kit, Xylocaine HCl For Spinal, L-Caine, Dilocaine, Nervocaine, Truxacaine, Anestacaine
Synonyms: Lidocaine injection, Lidocaine (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Lidocaine Topical Oral Solution 4%-MG 217 Topical
- Lidocaine Topical Oral Solution 4%-MG Plus Protein
- Lidocaine Topical Oral Solution 4%-MG217 Medicated Tar
- Lidocaine Topical Oral Solution 4%-Mg217 Sal-Acid Topical
- Lidocaine Topical Oral Solution 4%-Mi-Acid
- Lidocaine Topical Oral Solution 4%-Mi-Acid Double Strength
- Mexitil-Lidocaine Topical System
- Mexitil-Lidocaine viscous
- Mexitil-LidoCort
- Mexitil-Lidoderm
- Mexitil-Lidoderm Topical application
- Mexitil-Lidodextrapine
Lidocaine Topical Oral Solution 4% - Mexitil 
Lidocaine Topical Oral Solution 4% - Mexitil 
Lidocaine Topical Oral Solution 4% - Mexitil 
Lidocaine Topical Oral Solution 4% - Mexitil 
Lidocaine Topical Oral Solution 4% - Mexitil 
Lidocaine Topical Oral Solution 4% - Mexitil 
Lidocaine Topical Oral Solution 4% - Mexitil 
Lidocaine Topical Oral Solution 4% - Mexitil 
Lidocaine Topical Oral Solution 4% - Mexitil 
Lidocaine Topical Oral Solution 4% - Mexitil 
Lidocaine Topical Oral Solution 4% - Mexitil 
Lidocaine Topical Oral Solution 4% - Mexitil