LidoSite and Synjardy XR

• Generic Name: epinephrine / lidocaine
• Dosage Forms: Topical Iontophoretic Patch and Controller
• Other Brand Names: D-Care 100X, Lignospan Forte, Lignospan Standard, Xylocaine MPF With Epinephrine, Xylocaine With Epinephrine

LidoSite uses an active transdermal delivery technology known as iontophoresis, which administers medications through the skin via a mild electric current. The LidoSite system administers lidocaine and epinepherine using a patented electrotransport technology that enables the controlled delivery of medication over a predetermined period of time, from minutes to days. Topical anesthetic creams and patches can take up to an hour to numb the skin, while LidoSite works in 10 minutes. LidoSite has successfully completed clinical trials and has been found to significantly decrease pain from needle injections and similar procedures in both adults and children. Lidosite is intended to also address a strong need in adult applications. Its major impact is expected to be in the pediatric population, where pain associated with needlesticks, blood-draw procedures and immunizations is a major issue for the clinician, child and parent.

• Generic Name: empagliflozin / metformin
• Dosage Forms: tablet, extended release
• Other Brand Names: Synjardy, Synjardy XR

Synjardy XR is a combination medicine used with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Synjardy XR is also used to lower the risk of death from heart attack, stroke, or heart failure in adults with type 2 diabetes who also have heart disease.

Synjardy XR is not for treating type 1 diabetes.

Synjardy XR may also be used for purposes not listed in this medication guide.