Linaclotide and Tezacaftor/ivacaftor and ivacaftor

• Generic Name: linaclotide
• Dosage Forms: n.a.
• Other Brand Names: Linzess

Linaclotide works by increasing the secretion of chloride and water in the intestines, which can soften stools and stimulate bowel movements.

Linaclotide is used to treat chronic constipation, or chronic irritable bowel syndrome (IBS) in people who have had constipation as the main symptom.

Linaclotide may also be used for purposes not listed in this medication guide.

• Generic Name: ivacaftor / tezacaftor
• Dosage Forms: n.a.
• Other Brand Names: Symdeko, Symdeko 4-Week

Tezacaftor/ivacaftor and ivacaftor combination is used to treat cystic fibrosis (CF) in patients 12 years of age and older. It is only used for patients who have two copies of F508del mutation, or who have at least one mutation in their CF transmembrane conductance regulator (CFTR) gene. Your doctor will use a test to check for the mutation before you receive the medicine.

Tezacaftor/ivacaftor and ivacaftor is available only with your doctor's prescription.