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Lincomycin and PCE Dispertab

Determining the interaction of Lincomycin and PCE Dispertab and the possibility of their joint administration.

Check result:

Lincomycin <> PCE Dispertab

Relevance: 04.11.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using lincomycin together with erythromycin. Using these medications together may cause either drug to be less effective. Contact your doctor immediately if your infection worsens. You may need a dose adjustment if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Lincomycin derivatives and erythromycin have antagonistic effects in vitro. The mechanism is competitive binding of the 50S ribosomal subunit.

MANAGEMENT: Clindamycin or lincomycin should not be used concurrently with erythromycin.

References

Hardman JG, Gilman AG, Limbird LE eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 9th ed." New York, NY: McGraw-Hill (1995):
"Product Information. Cleocin (clindamycin)." Pharmacia and Upjohn, Kalamazoo, MI.

Lincomycin

Generic Name: lincomycin

Brand name: Lincocin, Lincorex, L-Mycin, Bactramycin

Synonyms: n.a.

What is Lincomycin?

PCE Dispertab

Generic Name: erythromycin

Brand name: EES. Granules, EES-400 Filmtab, EryPed 200, EryPed 400, Ery-Tab, Erythrocin Lactobionate, Erythrocin Stearate Filmtab, PCE Dispertab, E. E. S, EryPed, Erythrocin, Erythromycin Filmtabs, Erythromycin Lactobionate - IV

Synonyms: PCE Dispertab (Oral), PCE, PCE (Oral)

What is PCE Dispertab?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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