Lincomycin Hydrochloride and Ziac

• Generic Name: lincomycin
• Dosage Forms: n.a.
• Other Brand Names: Lincocin, Lincorex, L-Mycin, Bactramycin

Treatment of serious infections caused by susceptible staphylococci, Streptococcus pneumoniae, and other streptococci. Because of more potent antibacterial activity, clindamycin usually preferred when a lincosamide antibiotic indicated for treatment of these infections.

Reserve for treatment of serious infections when less toxic alternatives cannot be used (e.g., penicillin-allergic patients or other patients for whom a penicillin is inappropriate). Has been associated with potentially fatal colitis (see Superinfection/Clostridium difficile-associated Diarrhea and Colitis [CDAD] under Cautions); consider nature of the infection and suitability of less toxic alternatives (e.g., erythromycin).

May be used concomitantly with other anti-infectives when indicated.

Certain infections may require incision and drainage or other indicated surgical procedures in addition to anti-infective treatment; use of lincomycin does not eliminate need for surgical procedures when indicated.

Do not use for treatment of meningitis because of inadequate CNS penetration following parenteral administration.

• Generic Name: bisoprolol / hydrochlorothiazide
• Dosage Forms: tablet, film coated
• Other Brand Names: Ziac

Ziac contains a combination of hydrochlorothiazide and bisoprolol. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Bisoprolol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Ziac is used to treat high blood pressure (hypertension).

Ziac may also be used for purposes not listed in this medication guide.