Linzess and Unithroid

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Linaclotide may cause diarrhea, which may affect the absorption of any other oral medication you may take. If you develop diarrhea, some of your medications such as levothyroxine may not work as well. Contact your doctor if you experience signs and symptoms of reduced thyroid function such as fatigue; sluggishness; constipation; depression; hoarseness; unexplained weight gain; sensitivity to cold; pale, dry skin; muscle aches, weakness, or tenderness; joint pain, stiffness, or swelling; heavier than normal menstruation periods; or brittle fingernails and hair. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: The efficacy of drugs with a narrow therapeutic index, such as levothyroxine, that are absorbed in the intestinal tract may be reduced if severe diarrhea occurs with linaclotide treatment. Linaclotide has been associated with severe and prolonged diarrhea.

MANAGEMENT: Caution and monitoring for altered efficacy is recommended during concomitant use.

Linzess

Generic Name: linaclotide

Brand name: Linzess

Synonyms: n.a.

What is Linzess?

Unithroid

Generic Name: levothyroxine

Brand name: Euthyrox, Levoxyl, Synthroid, Tirosint, Unithroid, Levothroid, Tirosint-Sol

Synonyms: Unithroid (Oral)

What is Unithroid?