Lioresal Intrathecal and Lorcaserin Hydrochloride

• Generic Name: baclofen
• Dosage Forms: Tablets
• Other Brand Names: Gablofen, Lioresal, Lioresal Intrathecal, FIRST Baclofen, Ozobax

Intrathecal baclofen is used to help relax certain muscles in your body. It relieves the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, cerebral palsy, or certain injuries to the spine. Intrathecal baclofen does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition.

Intrathecal baclofen acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects.

This medicine is delivered by a drug pump directly into the spinal fluid of your back. A doctor will surgically place the pump and monitor the dose of the medication that is delivered by the pump. The dose of intrathecal baclofen will be different for different patients and will depend on the type of muscle tightness that you have.

Intrathecal baclofen is given only by or under the direct supervision of a doctor.

• Generic Name: lorcaserin
• Dosage Forms: n.a.
• Other Brand Names: Belviq, Belviq XR

Adjunct to caloric restriction and increased physical activity in the chronic management of obesity.

Used in patients who are obese (pretreatment body mass index [BMI] ≥30 kg/m2); also used in overweight patients with pretreatment BMI ≥27 kg/m2 in the presence of a weight-related risk factor or disease (e.g., hypertension, type 2 diabetes mellitus, dyslipidemia).

Indicated only for monotherapy; safety and efficacy in combination with other weight loss products (prescription drugs [e.g., phentermine], OTC drugs, herbal preparations) not established.

Long-term effects on cardiovascular morbidity and mortality associated with obesity not established; safety and efficacy beyond 2 years of use not established.