Lithium and Potassium Chloride in Sodium Chloride
Determining the interaction of Lithium and Potassium Chloride in Sodium Chloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using sodium chloride together with lithium may decrease the effects of lithium. You should avoid very high and very low sodium consumption. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Large sodium intake may decrease serum lithium levels. Sodium restriction may increase lithium levels. The mechanism is increased renal excretion of lithium in the setting of high salt loads and vice versa.
MANAGEMENT: Patients taking lithium should avoid very high and very low sodium consumption. Monitoring of lithium levels is recommended.
- Bleiweiss H "Salt supplements with lithium." Lancet 1 (1970): 416
- Baer L, Platman SR, Kassir S, Fieve RR "Mechanisms of renal lithium handling and their relationship to mineralocorticoids: a dissociation between sodium and lithium ions." J Psychiatr Res 8 (1971): 91-105
Generic Name: lithium
Brand name: Lithobid, Eskalith, Lithonate, Lithotabs, Eskalith-CR
Synonyms: n.a.
Generic Name: potassium chloride / sodium chloride
Brand name: Buffered Salt, Thermotabs
Synonyms: Potassium chloride and sodium chloride
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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