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Lithium Controlled-Release and Extended-Release Tablets and Theraflu Daytime Severe Cold

Determining the interaction of Lithium Controlled-Release and Extended-Release Tablets and Theraflu Daytime Severe Cold and the possibility of their joint administration.

Check result:
Lithium Controlled-Release and Extended-Release Tablets <> Theraflu Daytime Severe Cold
Relevance: 05.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Lithium may decrease the pressor effect of some sympathomimetic agents. The mechanism is unknown. Also, dopamine may increase the plasma clearance of lithium. Plasma lithium levels may be decreased.

References
  • Rosenblatt JE, Lake CR, van Kammen DP, Ziegler MG, Bunney WE Jr "Interactions of amphetamine, pimozide, and lithium on plasma norepineophrine and dopamine-beta-hydroxylase in schizophrenic patients." Psychiatry Res 1 (1979): 45-52
  • Macdonald TM, Cotton M, Prescott LF "Low dose dopamine in lithium poisoning." Br J Clin Pharmacol 26 (1988): 195-7
  • Grof E, Brown GM, Grof P, Van Loon GR "Effects of lithium administration on plasma catecholamines." Psychiatry Res 19 (1986): 87-92
Lithium Controlled-Release and Extended-Release Tablets

Generic Name: lithium

Brand name: Lithobid, Eskalith, Lithonate, Lithotabs, Eskalith-CR

Synonyms: Lithium

Theraflu Daytime Severe Cold

Generic Name: acetaminophen / phenylephrine

Brand name: Alka-Seltzer Plus Cold and Sinus, Contac Cold+Flu Non-Drowsy, Excedrin Sinus Headache Caplet, Mapap Sinus Congestion and Pain, QlearQuil Daytime Sinus & Congestion, Robitussin Nasal Relief, Sinus Congestion and Pain Daytime Cool Ice, Sinus Pain & Pressure, Sudafed PE Sinus Headache, Theraflu Daytime Severe Cold, Tylenol Sinus Congestion and Pain, Congespirin Aspirin Free, Neo Citran Extra Strength Cold and Sinus, Mapap Sinus PE, Tylenol Sinus Congestion Daytime, Excedrin Sinus Headache, Non-Pseudo Sinus Pain & Pressure, Robitussin Peak Cold Nasal Relief, Sudafed PE Pressure Plus Pain, Contact Cold and Flu Day, Tylenol Sinus + Headache Day, Vicks Sinex Daytime, Mygrex, Acetaminophen Congestion and Pain, QlearQuil Sinus & Congestion, Vicks DayQuil Sinex

Synonyms: Acetaminophen and phenylephrine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.