Lithium Salts and Pms-Sodium Polystyrene Sulfonate
Determining the interaction of Lithium Salts and Pms-Sodium Polystyrene Sulfonate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using lithium together with sodium polystyrene sulfonate can decrease the effects of lithium. Contact your doctor if your condition worsens. You should consider separating the times of administration of sodium polystyrene sulfonate and lithium by several hours if possible. You may need a dose adjustment or special tests if your use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Coadministration with cation-exchange resins may delay and/or reduce the absorption of lithium. The resins are not totally selective for potassium and may bind to other cations such as lithium. This binding may also reduce the potassium exchange capability of the cation-exchange resins.
MANAGEMENT: Patients should consider separating the times of administration of the cation-exchange resin and lithium by several hours if possible.
- "Product Information. Kayexalate (sodium polystyrene sulfonate)." Sanofi Winthrop Pharmaceuticals, New York, NY.
- "Product Information. Resonium Calcium (calcium polystyrene sulfonate)." Sanofi-Synthelabo Canada Inc, Markham, ON.
Generic Name: lithium
Brand name: Lithobid, Eskalith, Lithonate, Lithotabs, Eskalith-CR
Synonyms: Lithium
Generic Name: sodium polystyrene sulfonate
Brand name: Kalexate, Kayexalate, Kionex
Synonyms: Sodium polystyrene sulfonate, Sodium Polystyrene Sulfonate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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