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Lithium Syrup and Oral Solution and Psyllium Powder

Determining the interaction of Lithium Syrup and Oral Solution and Psyllium Powder and the possibility of their joint administration.

Check result:
Lithium Syrup and Oral Solution <> Psyllium Powder
Relevance: 04.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

A case has been reported in which a woman was admitted to a psychiatric unit due to "behavioral changes" probably due to low lithium levels caused by ingestion of psyllium. Psyllium was believed to have inhibited the absorption of lithium from the gastrointestinal tract. Psyllium should be ingested at least 2 hours before or 2 hours after the lithium dose.

References
  • Perlman BB "Interaction between lithium salts and ispaghula husk [letter]." Lancet 335 (1990): 416
  • "Product Information. Metamucil (psyllium)." Procter and Gamble Pharmaceutic, Cincinnati, OH.
Lithium Syrup and Oral Solution

Generic Name: lithium

Brand name: Lithobid, Eskalith, Lithonate, Lithotabs, Eskalith-CR

Synonyms: Lithium

Psyllium Powder

Generic Name: psyllium

Brand name: Hydrocil, Konsyl, Laxmar, Metamucil, Natural Fiber Therapy, Reguloid, Fiberall, Syllact, Modane Bulk, V-Lax, Perdiem Fiber Powder, Konsyl-Orange, Konsyl-D, Maalox Daily Fiber Therapy, Cilium, Alramucil, Serutan, Laxative Natural, Genfiber, Fiber Eze, Konsyl for Kids, Laxmar Orange, Metamucil Orange Smooth Texture, Metamucil Orange Smooth Texture Sugar Free, Metamucil Unflavored Coarse Milled Original, Fiber Therapy, Metamucil Orange Coarse Milled Original, Metamucil Unflavored Smooth Texture, Metamucil Berry Burst Smooth Texture, Laxmar Sugar Free, Konsyl Orange Sugar-free, Metamucil Pink Lemonade Smooth Texture Sugar-Free, Metamucil Original Texture Regular, Metamucil MultiHealth Fiber, Metamucil MultiHealth Fiber Sugar-free, Reguloid Sugar Free, Reguloid Orange Smooth, Reguloid Sugar Free Orange Smooth, Konsyl Sugar Free Orange With Stevia

Synonyms: Psyllium

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.