Lithobid and Nymalize (Nimodipine Oral Solution)
Determining the interaction of Lithobid and Nymalize (Nimodipine Oral Solution) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Before taking niMODipine, tell your doctor if you also use lithium. You may need dose adjustments or special tests in order to safely take both medications together. You should notify your doctor if you have symptoms such as diarrhea, vomiting, drowsiness, tremor, thirst, lack of coordination, or muscle weakness. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor first.
Professional:MONITOR: Several case reports have suggested that the combination of lithium and calcium channel blockers may cause neurotoxicity and psychiatric effects such as psychosis. The mechanism is unknown. Data have been conflicting. Cases have been reported for diltiazem and verapamil.
MANAGEMENT: Patients who must take both drugs should be closely monitored for adverse neurologic and psychiatric effects. Patients should be advised to notify their physician if they experience symptoms of possible lithium toxicity such as drowsiness, dizziness, confusion, ataxia, vomiting, diarrhea, thirst, blurry vision, tinnitus, or tremor.
- Binder EF, Cayabyab L, Ritchie DJ, Birge SJ "Diltiazem-induced psychosis and a possible diltiazem-lithium interaction." Arch Intern Med 151 (1991): 373-4
- Valdiserri EV "A possible interaction between lithium and diltiazem: case report." J Clin Psychiatry 46 (1985): 540-1
- "Product Information. Eskalith (lithium)." SmithKline Beecham, Philadelphia, PA.
Generic Name: lithium
Brand name: Lithobid, Eskalith, Lithonate, Lithotabs, Eskalith-CR
Synonyms: n.a.
Generic Name: nimodipine
Brand name: Nymalize, Nimotop
Synonyms: Nymalize
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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